BDBM347645 6-[2-[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl]ethynyl]-1H-pyrrolo[2,3-b]pyridine::US9790203, Example 15

SMILES Cn1cc(c(n1)-c1ccc(cc1)C#Cc1ccc2cc[nH]c2n1)-c1ccncc1

InChI Key InChIKey=RRDKHZIOLKZGDS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347645   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie

US Patent

LigandBDBM347645(6-[2-[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/9/2019
Entry Details
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