BDBM347635 2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)ethynyl)pyridine::US9790203, Example 2

SMILES Cn1cc(c(n1)-c1ccc(cc1)C#Cc1ccccn1)-c1ccncc1

InChI Key InChIKey=WEMTXDFFLVYFKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347635   

LigandPNGBDBM347635(2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...)
Affinity DataIC50: 100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

LigandPNGBDBM347635(2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed