BDBM347427 US10869871, ID # SW209332::US20230285402, ID # SW209332::US9789116, SW209332

SMILES Nc1c(sc2nc(cc(-c3ccccc3)c12)-c1cccs1)[S+]([O-])CCCC#N

InChI Key InChIKey=NKABCRZZRGTSIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347427   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347427(US9789116, SW209332 | US10869871, ID # SW209332 | ...)
Affinity DataIC50: 8.72nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347427(US9789116, SW209332 | US10869871, ID # SW209332 | ...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed