BDBM347361 US10301320, ID SW206977::US10869871, ID # SW206977::US20230285402, ID # SW206977::US9789116, SW206977

SMILES CCCNC(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1

InChI Key InChIKey=ULMPRHYHVRJCDO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 347361   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347361(US9789116, SW206977 | US10301320, ID SW206977 | US...)
Affinity DataIC50: 7.50E+3nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347361(US9789116, SW206977 | US10301320, ID SW206977 | US...)
Affinity DataIC50: 7.50E+3nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347361(US9789116, SW206977 | US10301320, ID SW206977 | US...)
Affinity DataIC50: 7.50E+3nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Case Western Reserve University

US Patent
LigandPNGBDBM347361(US9789116, SW206977 | US10301320, ID SW206977 | US...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed