BDBM3473 1-benzyl-3-[6-(2,6-dichlorophenyl)-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea::6-arylpyrido[2,3-d]pyrimidine deriv. 55::CHEMBL51485

SMILES CN1CCN(CCCNc2ncc3cc(c(NC(=O)NCc4ccccc4)nc3n2)-c2c(Cl)cccc2Cl)CC1

InChI Key InChIKey=XARWOHKDCBRPBQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3473   

LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 62nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 30nMAssay Description:Inhibition of chicken c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3473(CHEMBL51485 | 1-benzyl-3-[6-(2,6-dichlorophenyl)-2...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed