BDBM347265 US10202411, Compound 327

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CF)[C@H]1O

InChI Key InChIKey=TYHVYTTVKNXRFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347265   

TargetGenome polyprotein(HCV)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347265(US10202411, Compound 327)
Affinity DataIC50: 250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetGenome polyprotein [S283T](HCV)
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM347265(US10202411, Compound 327)
Affinity DataIC50: 250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent