BDBM347126 2-(4-(methyl(3-(4-methylpiperazin-1- yl)phenyl)amino)-3-(trifluoromethyl) phenoxy)pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 133::US10208039, Example 133

SMILES CN(c1cccc(c1)N1CCN(C)CC1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1C(F)(F)F

InChI Key InChIKey=YKRZXSSMPBSNJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347126   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM347126(2-(4-(methyl(3-(4-methylpiperazin-1- yl)phenyl)ami...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent