BDBM347022 US10202388, Compound 23A-2::US10202388, Compound 26A-3

SMILES O[C@H](CC1c2c(cccc2F)-c2cncn12)C12CC3CC(C1)[C@H](O)C(C3)C2

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 347022   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347022(US10202388, Compound 26A-3 | US10202388, Compound ...)
Affinity DataIC50: 5.50E+3nMAssay Description:The compounds described in this disclosure were dissolved in 10% DMSO to predefined concentration. All of the reactions were conducted at room temper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347022(US10202388, Compound 26A-3 | US10202388, Compound ...)
Affinity DataIC50: 100nMAssay Description:The compounds described in this disclosure were dissolved in 10% DMSO to predefined concentration. All of the reactions were conducted at room temper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347022(US10202388, Compound 26A-3 | US10202388, Compound ...)
Affinity DataIC50: 300nMAssay Description:The TDO2 enzymatic assay was performed by UV absorption using a recombinant TDO2 and L-Tryptophan substrate. The UV absorption signal at 321 nm is co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent