BDBM3463 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(2-methylpiperidin-1-yl)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea::6-arylpyrido[2,3-d]pyrimidine deriv. 45

SMILES CC1CCCCN1CCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=TWRMMAAINFMTFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3463   

LigandPNGBDBM3463(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(2-me...)
Affinity DataIC50: 730nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3463(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(2-me...)
Affinity DataIC50: 60nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3463(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(2-me...)
Affinity DataIC50: 16nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed