BDBM346290 US10202377, Compound 126

SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccncc1)C1CCCCC1

InChI Key InChIKey=BDIHZYLLAUQGAQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346290   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM346290(US10202377, Compound 126)
Affinity DataIC50: 1.00E+4nMAssay Description:The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Samumed

US Patent
LigandPNGBDBM346290(US10202377, Compound 126)
Affinity DataEC50:  9.99E+3nMAssay Description:Compound Screening: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:2, 11-point d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent