BDBM346249 2-[2-chloro-4-(2-methyl-4-pyridyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 12

SMILES Cc1cc(ccn1)-c1nc(Cl)nc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key InChIKey=IZCSRAGIUFPFFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346249   

TargetProtein Wnt-3a(Mouse)
Redx Pharma

US Patent
LigandPNGBDBM346249(2-[2-chloro-4-(2-methyl-4-pyridyl)pyrrolo[2,3-d]py...)
Affinity DataIC50: 1nMAssay Description:Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent