BDBM346247 2-[2-methyl-4-(2-methyl-4-pyridyl)pyrrolo[2,3-d]pyrimidin-7-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 10

SMILES Cc1cc(ccn1)-c1nc(C)nc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key InChIKey=WJXVVAPPQPDCSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346247   

TargetProtein Wnt-3a(Mouse)
Redx Pharma

US Patent
LigandPNGBDBM346247(2-[2-methyl-4-(2-methyl-4-pyridyl)pyrrolo[2,3-d]py...)
Affinity DataIC50: 1nMAssay Description:Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Mouse)
Redx Pharma

US Patent
LigandPNGBDBM346247(2-[2-methyl-4-(2-methyl-4-pyridyl)pyrrolo[2,3-d]py...)
Affinity DataIC50: 0.320nMAssay Description:Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent