BDBM346213 US10202373, Compound I-27::US10202373, Example 12

SMILES O=C(Cc1nnn[nH]1)Nc1cc(ccn1)-c1cncc2n(ccc12)S(=O)(=O)C1CC1

InChI Key InChIKey=DELDVFSVSXJSKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346213   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM346213(US10202373, Example 12 | US10202373, Compound I-27)
Affinity DataIC50: 30nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent