BDBM346196 US10202373, Compound I-8::US10202373, Example 9

SMILES CC(=O)Nc1cc(c(F)cn1)-c1cncc2n(ccc12)S(=O)(=O)C1CC1

InChI Key InChIKey=XUWBHJANIKJVPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346196   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM346196(US10202373, Example 9 | US10202373, Compound I-8)
Affinity DataIC50: 30nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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