BDBM346173 US10202371, Example 3

SMILES COc1ccc(cc1)[C@@H]1OC(=O)N([C@H]1CO)c1cc(nc(n1)N1CCOCC1)-c1cnc(N)nc1C(F)(F)F

InChI Key InChIKey=HCGYTLSSUHSQGE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 346173   

LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 5nMAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 7nMAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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TargetSerine/threonine-protein kinase mTOR(Human)
Novartis

US Patent
LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 850nMAssay Description:TR-FRET assays for protein kinases uses a long-lifetime lanthanide Terbium or Europium chelates as the donor species which overcome interference by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 74nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 33nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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LigandPNGBDBM346173(US10202371, Example 3)
Affinity DataIC50: 6nMAssay Description:AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent