BDBM346000 N-(5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazol-4-ylmethyl)-N-(2-dimethylamino-ethyl)-2-(4-ethyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-acetamide::US10202368, Example 77

SMILES CCN1CCOc2c(C1)cccc2NCC(=O)N(CCN(C)C)C(C)c1c(Cl)[nH]nc1C(F)(F)F

InChI Key InChIKey=KMWYZANNNLTNHS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346000   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM346000(N-(5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazol-...)
Affinity DataEC50:  280nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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