BDBM345999 N-(2-Dimethylamino-ethyl)-2-(4-ethyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-N-(2-trifluoromethyl-thiazol-5-ylmethyl)-acetamide::US10202368, Example 76

SMILES CCN1CCOc2c(C1)cccc2NCC(=O)N(CCN(C)C)Cc1cnc(s1)C(F)(F)F

InChI Key InChIKey=SHUAXPOVHCEWNS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345999   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345999(N-(2-Dimethylamino-ethyl)-2-(4-ethyl-2,3,4,5-tetra...)
Affinity DataEC50:  430nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent