BDBM345985 2-(4-Cyclopropylmethyl-5-oxo-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-N-(2-isopropylamino-ethyl)-N-(2-trifluoromethyl-benzyl)-acetamide::US10202368, Example 62

SMILES CC(C)NCCN(Cc1ccccc1C(F)(F)F)C(=O)CNc1cccc2c1OCCN(CC1CC1)C2=O

InChI Key InChIKey=OLHAMCIMZGQDBA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345985   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345985(US10202368, Example 62 | 2-(4-Cyclopropylmethyl-5-...)
Affinity DataEC50:  5nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent