BDBM345980 2-(4-Ethyl-5-oxo-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-N-(3-trifluoromethyl-pyridin-2-ylmethyl)-acetamide::US10202368, Example 57

SMILES CCN1CCOc2c(NCC(=O)N(CCN3CCCC3)Cc3ncccc3C(F)(F)F)cccc2C1=O

InChI Key InChIKey=YTQVLTCZGPIOFM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345980   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345980(US10202368, Example 57 | 2-(4-Ethyl-5-oxo-2,3,4,5-...)
Affinity DataEC50:  60nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent