BDBM345970 N-(3-Chloro-pyridin-2-ylmethyl)-2-(4-cyclopropylmethyl-1-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-9-ylamino)-N-(2-dimethylamino-ethyl)-acetamide::US10202368, Example 45

SMILES CN(C)CCN(Cc1ncccc1Cl)C(=O)CNc1cccc2c1N(C)CCN(CC1CC1)C2=O

InChI Key InChIKey=PTTBBRDGHQHDMQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345970   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345970(US10202368, Example 45 | N-(3-Chloro-pyridin-2-ylm...)
Affinity DataEC50:  50nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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