BDBM345944 N-(2,6-Difluoro-benzyl)-N-(2-dimethylamino-ethyl)-2-(4-isobutyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-acetamide::US10202368, Example 19

SMILES CC(C)CN1CCOc2c(C1)cccc2NCC(=O)N(CCN(C)C)Cc1c(F)cccc1F

InChI Key InChIKey=GMACMDDQXVTETK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345944   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345944(US10202368, Example 19 | N-(2,6-Difluoro-benzyl)-N...)
Affinity DataEC50:  12nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
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Date in BDB:
9/2/2019
Entry Details
Go to US Patent