BDBM345937 N-(2,4-Difluoro-benzyl)-2-(4-isobutyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-9-ylamino)-N-(2-pyrrolidin-1-yl-ethyl)-acetamide::US10202368, Example 12

SMILES CC(C)CN1CCOc2c(C1)cccc2NCC(=O)N(CCN1CCCC1)Cc1ccc(F)cc1F

InChI Key InChIKey=LEGJURAGEHJGED-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345937   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM345937(US10202368, Example 12 | N-(2,4-Difluoro-benzyl)-2...)
Affinity DataEC50:  14nMAssay Description:The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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