BDBM345799 N-(2-(2,4-difluoro-6- methylphenoxy)-6-(1-methyl-6-oxo- 1,6-dihydropyridin-3-yl)pyrimidin- 4-yl)propane-1-sulfonamide::US10202360, Example 344

SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cc(F)cc2F)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=TUBXORYMDVRFHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345799   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345799(US10202360, Example 344 | N-(2-(2,4-difluoro-6- me...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent