BDBM345514 N-(2-(benzofuran-4-yloxy)-6-(1,5- dimethyl-6-oxo-1,6-dihydropyridin- 3-yl)pyrimidin-4-yl)propane-2- sulfonamide::US10202360, Example 59

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2cccc3occc23)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=PCEPSAOYJJRGGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345514   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM345514(US10202360, Example 59 | N-(2-(benzofuran-4-yloxy)...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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