BDBM345477 Butane-1-sulfonic acid [2-(2-cyano- 6-methyl-phenoxy)-6-(1,5-dimethyl- 6-oxo-1,6-dihydro-pyridin-3-yl)- pyrimidin-4-yl]-amide::US10202360, Example 22

SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=PMRXWTIFRSPRCA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345477   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent

LigandBDBM345477(US10202360, Example 22 | Butane-1-sulfonic acid [2...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2019
Entry Details
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