BDBM345456 Propane-2-sulfonic acid [2-(2,5-dichloro-phenoxy)-6-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-pyrimidin-4-yl]-amide::US10202360, Example 1

SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2cc(Cl)ccc2Cl)n1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=QPOFQBNBLDDZCO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345456   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent

LigandBDBM345456(US10202360, Example 1 | Propane-2-sulfonic acid [2...)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL