BDBM34542 US8546380, 220::US8633188, 220
SMILES CC1(CCSC(N)=N1)c1cccc(c1)C(=O)Nc1ccc(Cl)cn1
InChI Key InChIKey=AKLATASKTPLNJX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 34542
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of recombinant human BACE1 (43 to 454 residues) expressed in Escherichia coli BL21 (DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu fluorogenic pept...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells expressing wild type betaAPP assessed as reduction in amyloidbeta (1 to 40 residues) level incubated for 2...More data for this Ligand-Target Pair