BDBM345391 1-cyclobutyl-4-[1-(3,5-dimethylphenyl)sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 56

SMILES Cc1cc(C)cc(c1)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=IGOQFTHTYAASLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345391   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM345391(1-cyclobutyl-4-[1-(3,5-dimethylphenyl)sulfonyl-4,5...)
Affinity DataIC50: 0.0880nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent