BDBM345389 1-cyclobutyl-4-[1-(3-phenylphenyl)sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 54

SMILES O=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=RFHABYMCPAIKCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345389   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM345389(1-cyclobutyl-4-[1-(3-phenylphenyl)sulfonyl-4,5-dih...)
Affinity DataIC50: 0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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