BDBM345370 1-cyclobutyl-4-[1-(3-cyclopropylphenyl)sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 35

SMILES O=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1cccc(c1)C1CC1

InChI Key InChIKey=NFIMKBZSGOEJID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345370   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM345370(1-cyclobutyl-4-[1-(3-cyclopropylphenyl)sulfonyl-4,...)
Affinity DataIC50: 0.0870nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent