BDBM345363 1-cyclobutyl-4-[1-[4-(1-methylpyrazol-3-yl)phenyl]sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 28

SMILES Cn1ccc(n1)-c1ccc(cc1)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=PBCDNKTVKKINRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345363   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM345363(1-cyclobutyl-4-[1-[4-(1-methylpyrazol-3-yl)phenyl]...)
Affinity DataIC50: 0.0490nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
9/2/2019
Entry Details
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