BDBM345357 1-[1-[4-(3-chlorophenyl)phe-nyl]sulfonyl-4,5-dihydroimidazol-2-yl]-4-cyclobutyl-piperazine::US10202354, Example 22

SMILES Clc1cccc(c1)-c1ccc(cc1)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=QCCBUARERXTMMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345357   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandPNGBDBM345357(1-[1-[4-(3-chlorophenyl)phe-nyl]sulfonyl-4,5-dihyd...)
Affinity DataIC50: 0.120nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
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