BDBM344864 1-(2-cyclobutyl-1-hydroxy-::1-(2-cyclobutyl-1-hydroxy-2-oxoethyl)-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 166

SMILES OC(N1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1F)C(=O)C1CCC1

InChI Key InChIKey=MLSYSOODFPTIID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344864   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344864(1-(2-cyclobutyl-1-hydroxy-2-oxoethyl)-3-[1-(2-fluo...)
Affinity DataIC50: 435nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent