BDBM344724 1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxazol-4-ylmethyl)imidazolidin-2-one::US9783527, Example 26

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(Cc2cocn2)C1=O

InChI Key InChIKey=KYXKKYKXKUCVDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 344724   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344724(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxaz...)
Affinity DataIC50: 382nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

LigandPNGBDBM344724(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxaz...)
Affinity DataIC50: 517nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent