BDBM344716 1-{2-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl]-2-oxoethyl}-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 18

SMILES F[C@H]1C[C@@H](N(C1)C(=O)CN1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1F)c1cc(F)ccc1F

InChI Key InChIKey=BSAOILPZFPSWQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344716   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344716(1-{2-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50: 578nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent