BDBM344690 3-[(2S)-4-[(3-ethoxy-1-ethyl- 1H-pyrazol-4-yl)sulfonyl]-8- fluoro-6-{[(2,2,2-trifluoro- 1,1- dimethylethoxy)carbonyl]ami- no}-3,4-dihydro-2H-1,4- benzoxazin-2-yl]propanoic acid::US9783511, 29D

SMILES CCOc1nn(CC)cc1S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2c(F)cc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=APZZAGNGYBLILS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344690   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344690(3-[(2S)-4-[(3-ethoxy-1-ethyl- 1H-pyrazol-4-yl)sulf...)
Affinity DataIC50: 7.92nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
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