BDBM344677 3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6- [({[1- (trifluoromethyl)cyclohexyl] oxy}carbonyl)amino]-3,4- dihydro-2H-1,4-benzoxazin- 2-yl}propanoic acid::US9783511, 24E

SMILES COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)OC3(CCCCC3)C(F)(F)F)cc12

InChI Key InChIKey=HYNWJRVVRIPMTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344677   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344677(3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6-...)
Affinity DataIC50: 4.71nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
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