BDBM344676 3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6- [({[(1S or 1R)-1,2,2- trimethylpropyl]oxy}cxarbonyl) amino]-3,4-dihydro-2H- 1,4-benzoxazin-2- yl}propanoic acid::US9783511, 24D

SMILES COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)O[C@H](C)C(C)(C)C)cc12

InChI Key InChIKey=LUZUDVIQTNQBDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344676   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344676(3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6-...)
Affinity DataIC50: 3.73nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent