BDBM344675 3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6- [({[(1S or 1R)-1,2,2- trimethylpropyl]oxy}carbonyl) amino]-3,4-dihydro-2H- 1,4-benzoxazin-2- yl}propanoic acid::US9783511, 24C

SMILES COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)O[C@@H](C)C(C)(C)C)cc12

InChI Key InChIKey=LUZUDVIQTNQBDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344675   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344675(3-{(2S)-4-[(4-fluoro-3- methoxyphenyl)sulfonyl]-6-...)
Affinity DataIC50: 3.80nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent