BDBM344671 3-((S)-4-((4-fluoro-3-methoxyphenyl)sulfonyl)-6-(((((R)-1,1,1-trifluoro-3,3-dimethylbutan-2-yl)oxy)carbonyl)amino)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)propanoic acid ::US9783511, 23A

SMILES COc1cc(ccc1F)S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)O[C@H](C(C)(C)C)C(F)(F)F)cc12

InChI Key InChIKey=WUESEHVJKMIEIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344671   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344671(3-((S)-4-((4-fluoro-3-methoxyphenyl)sulfonyl)-6-((...)
Affinity DataIC50: 3.04nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
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