BDBM344554 (S or R)-2-methyl-3-((S)-6- ((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-4- ((5-(trifluoromethyl)pyridin- 3-yl)sulfonyl)-3,4-dihydro- 2H-benzo[b][1,4]oxazin-2- yl)propanoic acid::US9783511, 6CX

SMILES C[C@H](C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1cncc(c1)C(F)(F)F)C(O)=O

InChI Key InChIKey=JXFDQQJCQTVVJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344554   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344554((S or R)-2-methyl-3-((S)-6- ((((1,1,1-trifluoro-2-...)
Affinity DataIC50: 7.35nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
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