BDBM344550 (S or R)-3-((S)-4-((4-fluoro- 3-methylphenyl)sulfonyl)-6- ((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-3,4- dihydro-2H- benzo[b][1,4]oxazin-2-yl)-2- methylpropanoic acid::US9783511, 6CT

SMILES C[C@@H](C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(C)c1)C(O)=O

InChI Key InChIKey=JVXLXNYCRFGLAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344550   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344550((S or R)-3-((S)-4-((4-fluoro- 3-methylphenyl)sulfo...)
Affinity DataIC50: 7.96nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent