BDBM344544 (S or R)-3-((S)-4-((4-fluoro- 3-methoxyphenyl)sulfonyl)- 6-((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-3,4- dihydro-2H- benzo[b][1,4]oxazin-2-yl)-2- methylpropanoic acid::US9783511, 6CN

SMILES COc1cc(ccc1F)S(=O)(=O)N1C[C@H](C[C@H](C)C(O)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=PTBCSGKNGDYTQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344544   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344544((S or R)-3-((S)-4-((4-fluoro- 3-methoxyphenyl)sulf...)
Affinity DataIC50: 6.08nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent