BDBM344464 (S)-3-(6-((((1,1,1-trifluoro- 2-methylpropan-2- yl)oxy)carbonyl)amino)-4- ((3- (trifluoromethoxy)phenyl) sulfonyl)-3,4-dihydro-2H- benzo[b][1,4]oxazin-2- yl)propanoic acid::US9783511, 6S

SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CCC(O)=O)CN(c2c1)S(=O)(=O)c1cccc(OC(F)(F)F)c1)C(F)(F)F

InChI Key InChIKey=HDCQBMXRGIRQNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344464   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344464((S)-3-(6-((((1,1,1-trifluoro- 2-methylpropan-2- yl...)
Affinity DataIC50: 6nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent