BDBM344449 (S)-3-(4-((3-chloro-1-ethyl- 1H-pyrazol-4-yl)sulfonyl)- 6-((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)- 3,4-dihydro-2H- benzo[b][1,4]oxazin-2- yl)propanoic acid::US9783511, 6E

SMILES CCn1cc(c(Cl)n1)S(=O)(=O)N1C[C@H](CCC(O)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=OOGFNDOJBAOOFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344449   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344449((S)-3-(4-((3-chloro-1-ethyl- 1H-pyrazol-4-yl)sulfo...)
Affinity DataIC50: 6nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
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