BDBM344438 (S)-ethyl 3-(4-((3-chloro-4- fluorophenyl)sulfonyl)-6- ((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-3,4- dihydro-2H-benzo[b][1,4]oxazin- 2-yl)propanoate::US9783511, 3i

SMILES CCOC(=O)CC[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(Cl)c1

InChI Key InChIKey=JSGDLDVOFGLNTK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344438   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344438((S)-ethyl 3-(4-((3-chloro-4- fluorophenyl)sulfonyl...)
Affinity DataIC50: 7nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent