BDBM344431 (R and S)-ethyl 3-((S)-4-((4- fluoro-3- (trifluoromethyl)phenyl)sulfonyl)- 6-((((1,1,1-trifluoro-2- methylpropan-2- yl)oxy)carbonyl)amino)-3,4- dihydro-2H-benzo[b][1,4]oxazin- 2-yl)-2-methylpropanoate::US9783511, 3B::US9783511, 3H

SMILES CCOC(=O)[C@@H](C)C[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=CLVFSWROAOPIPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 344431   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344431(US9783511, 3B | (R and S)-ethyl 3-((S)-4-((4- fluo...)
Affinity DataIC50: 3nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM344431(US9783511, 3B | (R and S)-ethyl 3-((S)-4-((4- fluo...)
Affinity DataIC50: 8nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details
Go to US Patent