BDBM344426 US9783500, Compound (S)-19

SMILES CN[C@@H](C)c1cncc(OCc2ccc3ccc(N)nc3c2)c1

InChI Key InChIKey=PKYCUWKYSZUTFJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 344426   

TargetNitric oxide synthase, brain(Human)
Northwestern University

US Patent
LigandPNGBDBM344426(US9783500, Compound (S)-19)
Affinity DataKi:  46nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
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TargetNitric oxide synthase, brain(Rat)
Northwestern University

US Patent
LigandPNGBDBM344426(US9783500, Compound (S)-19)
Affinity DataKi:  50nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
Go to US Patent

TargetNitric oxide synthase, inducible(Human)
Northwestern University

US Patent
LigandPNGBDBM344426(US9783500, Compound (S)-19)
Affinity DataKi:  2.21E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
Go to US Patent

TargetNitric oxide synthase, brain(Mouse)
Northwestern University

US Patent
LigandPNGBDBM344426(US9783500, Compound (S)-19)
Affinity DataKi:  2.56E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
Go to US Patent