BDBM344277 N-[6-(4-acetylpiperazin-1-yl)-2-methoxypyridin-3-yl]-5,5-dimethyl-4-oxo-4,7-dihydro-5H-furo[2,3-c]pyran-3-carboxamide::US9777020, Example 171

SMILES COc1nc(ccc1NC(=O)c1coc2COC(C)(C)C(=O)c12)N1CCN(CC1)C(C)=O

InChI Key InChIKey=ZGHNQGBDTVTZFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344277   

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344277(N-[6-(4-acetylpiperazin-1-yl)-2-methoxypyridin-3-y...)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent