BDBM344248 N-{6-[(3S)-4-acetyl-3-(methoxymethyl)piperazin-1-yl]-2-(2-hydroxy-2-methylpropoxy)pyridin-3-yl}-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydrofuro[3,2-c]pyridine-3-carboxamide::US9777020, Example 142

SMILES COC[C@@H]1CN(CCN1C(C)=O)c1ccc(NC(=O)c2coc3CC(C)(C)NC(=O)c23)c(OCC(C)(C)O)n1

InChI Key InChIKey=RVFKGFICULXNDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344248   

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344248(N-{6-[(3S)-4-acetyl-3-(methoxymethyl)piperazin-1-y...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent